This urine cotinine (nicotine) test will determine the presence of cotinine/nicotine in the system. Cotinine is the metabolite or what is left after nicotine consumption and is the test of choice to evaluate active tobacco use or exposure to tobacco in many forms. Cotinine is more stable and has a longer life in the body than nicotine. However, nicotine is highly addictive and found in tobacco, cigarettes, and many other manufactured products such as e-cigarettes used for vaping. This test is a laboratory-based test and includes a screen and confirmation if necessary.